Sielken, Robert: search on Z-Library

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1

Driving Cancer Dose-Response Modeling with Data, Not Assumptions

Robert L. Sielken Jr.

Journal:

Year:

1990

Language:

english

File:

PDF, 147 KB

english, 1990

2

Improving Survivability of Intelligent Transportation Systems: Application-Level Intrusion Detection Case Study

Smith, Brian L., Sielken, Robert S.

Journal:

Transportation Research Record Journal of the Transportation Research Board

Year:

2000

File:

PDF, 677 KB

2000

3

Generating single-unit residue concentration distributions based on maximum likelihood estimation from composite data

Ciriaco Valdez-Flores, Larry R. Holden, Robert L. Sielken Jr.

Journal:

Year:

2002

Language:

english

File:

PDF, 125 KB

english, 2002

4

Confidence Limits for Global Optima Based on Heuristic Solutions to Difficult Optimization Problems: A Simulation Study

Monroe, Howard M., Sielken, Robert L.

Journal:

American Journal of Mathematical and Management Sciences

Year:

1984

Language:

english

File:

PDF, 8.90 MB

english, 1984

5

Life-table calculations of excess risk for incidence versus mortality: Ethylene oxide case study

Robert L. Sielken Jr., Ciriaco Valdez-Flores

Journal:

Regulatory Toxicology and Pharmacology

Year:

2009

Language:

english

File:

PDF, 582 KB

english, 2009

6

Overestimation Bias and Other Pitfalls Associated with the Estimated 99.9th Percentile in Acute Dietary Exposure Assessments

Christine F. Chaisson, Robert L. Sielken Jr., Darin K. Waylett

Journal:

Regulatory Toxicology and Pharmacology

Year:

1999

Language:

english

File:

PDF, 224 KB

english, 1999

7

Exact Confidence Intervals for Linear Combinations of Variance Components in Nested Classifications

Burdick, Richard K., Sielken, Robert L.

Journal:

Journal of the American Statistical Association

Year:

1978

Language:

english

File:

PDF, 574 KB

english, 1978

8

Calculating excess risk with age-dependent adjustment factors and cumulative doses: Ethylene oxide case study

Robert L. Sielken, Ciriaco Valdez Flores

Journal:

Regulatory Toxicology and Pharmacology

Year:

2009

Language:

english

File:

PDF, 315 KB

english, 2009

9

ES Series: Cancer Risk Assessment. 3. Cancer dose-response extrapolations

Sielken, Robert L.

Journal:

Environmental Science & Technology

Year:

1987

Language:

english

File:

PDF, 9.74 MB

english, 1987

10

Some issues in the quantitative modeling portion of cancer risk assessment

Sielken, Robert L.

Journal:

Regulatory Toxicology and Pharmacology

Year:

1985

Language:

english

File:

PDF, 523 KB

english, 1985

11

Exact Confidence Intervals for Linear Combinations of Variance Components in Nested Classifications

Richard K. Burdick and Robert L. Sielken, Jr.

Journal:

Journal of the American Statistical Association

Year:

1978

Language:

english

File:

PDF, 573 KB

english, 1978

12

Practical Linear Programming with Computer Applicationsby Michael O. Locks

Review by: Robert L. Sielken, Jr.

Journal:

Year:

1975

Language:

english

File:

PDF, 343 KB

english, 1975

13

Some implications for quantitative risk assessment if hormesis exists

Sielken, Robert L, Stevenson, Donald E

Journal:

Human & Experimental Toxicology

Year:

1998

Language:

english

File:

PDF, 136 KB

english, 1998

14

Cancer Dose-Response Modeling of Epidemiological Data on Worker Exposures to Aldrin and Dieldrin

Robert L. Sielken, Robert S. Bretzlaff, Ciriaco Valdez-Flores, Donald E. Stevenson, Geert de Jong

Journal:

Year:

1999

Language:

english

File:

PDF, 125 KB

english, 1999

15

Stopping times for stochastic approximation procedures

Robert L. Sielken

Journal:

Probability Theory and Related Fields

Year:

1973

Language:

english

File:

PDF, 373 KB

english, 1973

16

Practical Linear Programming with Computer Applications

Sielken, Robert L.

Journal:

Year:

1975

Language:

english

File:

PDF, 147 KB

english, 1975

17

Modeling Aggregate Exposures to Glycol Ethers from Use of Commercial Floor Products

Koontz, Michael, Price, Paul, Hamilton, John, Daggett, Daniel, Sielken, Robert, Bretzlaff, Robert, Tyler, Tipton

Journal:

International Journal of Toxicology

Year:

2006

Language:

english

File:

PDF, 312 KB

english, 2006

18

Quantitative risk assessment of exposures to butadiene in EU occupational settings based on the University of Alabama at Birmingham epidemiological study

Sielken, Robert L., Valdez-Flores, Ciriaco

Journal:

Regulatory Toxicology and Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.95 MB

english, 2013

19

A Distributional Approach to Characterizing Low-Dose Cancer Risk

John S. Evans, John D. Graham, George M. Gray, Robert L. Sielken Jr.

Journal:

Year:

1994

Language:

english

File:

PDF, 1.13 MB

english, 1994

20

Changes in Sensitivity to the Effects of Atrazine on the Luteinizing Hormone Surge in Female Sprague-Dawley Rats after Repeated Daily Doses: Correlation with Liver Enzyme Expression

Breckenridge, Charles B., Foradori, Chad D., Sawhney Coder, Pragati, Simpkins, James W., Sielken, Robert L., Handa, Robert J.

Journal:

Birth Defects Research

Year:

2017

Language:

english

File:

PDF, 917 KB

english, 2017

21

Quantitative cancer risk assessment based on NIOSH and UCC epidemiological data for workers exposed to ethylene oxide

Ciriaco Valdez-Flores, Robert L. Sielken Jr., M. Jane Teta

Journal:

Regulatory Toxicology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 307 KB

english, 2010

22

Butadiene cancer exposure–response modeling: Based on workers in the styrene–butadiene–rubber industry: Total leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia, and chronic myelogenous leukemia

Robert L. Sielken Jr., Ciriaco Valdez-Flores

Journal:

Regulatory Toxicology and Pharmacology

Year:

2011

Language:

english

File:

PDF, 931 KB

english, 2011

23

An approach for estimating ecological risks from organochlorine pesticides to terrestrial organisms at rocky mountain arsenal

Banton, Marcy I., Klingensmith, J. Scott, Barchers, Daniel E., Clifford, Philip A., Ludwig, David F., Macrander, A. Michael, Sielken, Robert L., Valdez‐Flores, Ciriaco

Journal:

Human and Ecological Risk Assessment An International Journal

Year:

1996

Language:

english

File:

PDF, 1.47 MB

english, 1996

24

Multiyear, through the season crop acreage estimation using estimated acreage in sample segments

Sielken, Robert L, Gbur, Edward E

Journal:

Communication in Statistics- Theory and Methods

Year:

1984

Language:

english

File:

PDF, 470 KB

english, 1984

25

Opportunities to improve quantitative risk assessment

Sielken, Robert L., Stevenson, Donald E.

Journal:

Human and Ecological Risk Assessment An International Journal

Year:

1997

Language:

english

File:

PDF, 875 KB

english, 1997

26

Sequencing with Setup Costs by Zero-One Mixed Integer Linear Programming

Sielken, Robert L.

Journal:

A I I E Transactions

Year:

1976

Language:

english

File:

PDF, 187 KB

english, 1976

27

Reconsideration of the genetic risk assessment for ethylene oxide exposures

R. Julian Preston, Timothy R. Fennell, A. Philip Leber, Robert L. Sielken Jr., James A. Swenberg

Journal:

Environmental and Molecular Mutagenesis

Year:

1995

Language:

english

File:

PDF, 1.31 MB

english, 1995

28

Comprehensive Realism's Weight-of-Evidence Based Distributional Dose-Response Characterization

Sielken, Robert L., Valdez-Flores, Ciriaco

Journal:

Human and Ecological Risk Assessment An International Journal

Year:

1996

Language:

english

File:

PDF, 1024 KB

english, 1996

29

Statistical Comparison of Carcinogenic Effects and Dose–Response Relationships in Rats and Mice for 2,4-Toluene Diamine to those Ascribed to Toluene Diisocyanate

Sielken, Robert L., Bretzlaff, Robert S., Valdez-Flores, Ciriaco, Parod, Ralph

Journal:

Human and Ecological Risk Assessment An International Journal

Year:

2012

Language:

english

File:

PDF, 534 KB

english, 2012

30

Development of a unit risk factor for nickel and inorganic nickel compounds based on an updated carcinogenic toxicity assessment

Joseph T. Haney Jr., Darrell D. McCant, Robert L. Sielken Jr., Ciriaco Valdez-Flores, Roberta L. Grant

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 401 KB

english, 2012

31

Assessment of safety/risk of chemicals: inception and evolution of the ADI and dose-response modeling procedures

Lu, Frank C., Sielken, Robert L.

Journal:

Toxicology Letters

Year:

1991

Language:

english

File:

PDF, 2.83 MB

english, 1991

32

Development of an inhalation unit risk factor for isoprene

Haney, Joseph T., Phillips, Tracie, Sielken, Robert L., Valdez-Flores, Ciriaco

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 941 KB

english, 2015

33

Association between Parkinson’s Disease and Cigarette Smoking, Rural Living, Well-Water Consumption, Farming and Pesticide Use: Systematic Review and Meta-Analysis

Breckenridge, Charles B., Berry, Colin, Chang, Ellen T., Sielken, Robert L., Mandel, Jack S., Guedes, Raul Narciso Carvalho

Journal:

Year:

2016

Language:

english

File:

PDF, 9.09 MB

english, 2016

34

Ethylene Oxide Cancer Risk Assessment Based on Epidemiological Data: Application of Revised Regulatory Guidelines

M. Jane Teta, Robert L. Sielken, Ciriaco Valdez-Flores

Journal:

Year:

1999

Language:

english

File:

PDF, 189 KB

english, 1999

35

Monograph: Reassessment of human cancer risk of aldrin/dieldrin

Donald E Stevenson, Earl F Walborg Jr, D Warner North, Robert L Sielken Jr, C.E Ross, Alan S Wright, Yong Xu, Lisa M Kamendulis, James E Klaunig

Journal:

Toxicology Letters

Year:

1999

Language:

english

File:

PDF, 447 KB

english, 1999

36

Misinterpretation of categorical rate ratios and inappropriate exposure–response model fitting can lead to biased estimates of risk: Ethylene oxide case study

Valdez-Flores, Ciriaco, Sielken, Robert L.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.14 MB

english, 2013

37

Updated Mortality Analyses of Pernis Epidemiological Data on Human Exposures to Aldrin and Dieldrin

Sielken,, Robert L., Bretzlaff, Robert S., Stevenson, Donald E., Jong, Geert de

Journal:

Human and Ecological Risk Assessment An International Journal

Year:

1998

Language:

english

File:

PDF, 193 KB

english, 1998

38

Risk Metrics and Cumulative Risk Assessment Methodology for the FQPA

Robert L. Sielken Jr.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2000

Language:

english

File:

PDF, 82 KB

english, 2000

39

Development of a cancer-based chronic inhalation reference value for hexavalent chromium based on a nonlinear-threshold carcinogenic assessment

Haney, Joseph T., Erraguntla, Neeraja, Sielken, Robert L., Valdez-Flores, Ciriaco

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 318 KB

english, 2012

40

The SOT Task Force's Response to the NCTR Letter

BRUCE, ROBERT D.., CARLTON, WILLIAM W., CLAYSON, DAVID, FERBER, KELVIN H., HUGHES, DONALD H., SALSBURG, DAVID S., SMITH, JERRY M., BROWN, W. RAY, CRANMER, MORRIS F., SIELKEN, ROBERT L., VAN RYZIN, JOH

Journal:

Toxicological Sciences

Year:

1983

Language:

english

File:

PDF, 418 KB

english, 1983

41

Statistical evaluations reflecting the skewness in the distribution of TCDD levels in human adipose tissue

Robert L. Sielken Jr.

Journal:

Year:

1987

Language:

english

File:

PDF, 209 KB

english, 1987

42

Consideration of Rat Chronic Progressive Nephropathy in Regulatory Evaluations for Carcinogenicity

Hard, G. C., Banton, M. I., Bretzlaff, R. S., Dekant, W., Fowles, J. R., Mallett, A. K., McGregor, D. B., Roberts, K. M., Sielken, R. L., Valdez-Flores, C., Cohen, S. M.

Journal:

Toxicological Sciences

Year:

2013

Language:

english

File:

PDF, 867 KB

english, 2013

43

Supplement 1 || Modeling to Incorporate Defense Mechanisms into the Estimation of Dose Responses

Robert L. Sielken, Jr. and Donald E. Stevenson

Journal:

Environmental Health Perspectives

Year:

1998

Language:

english

File:

PDF, 656 KB

english, 1998

44

A comprehensive review of occupational and general population cancer risk: 1,3-Butadiene exposure–response modeling for all leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia, chronic myelogenous leukemia, myeloid neoplasm and lymphoid neoplasm

Sielken, Robert L., Valdez-Flores, Ciriaco

Journal:

Chemico-Biological Interactions

Year:

2015

Language:

english

File:

PDF, 838 KB

english, 2015

45

Supplement 1. Agricultural exposures and cancer || Statistical inferences about the mechanism of action in carcinogenicity studies

Robert L Sielken Jr, Ciriaco Valdez-Flores, Larry R Holden, Charles Breckenridge and James Stevens

Journal:

Scandinavian Journal of Work Environment & Health

Year:

2005

Language:

english

File:

PDF, 729 KB

english, 2005

46

PBPK-Based Probabilistic Risk Assessment for Total Chlorotriazines in Drinking Water

Breckenridge, Charles B., Campbell, Jerry L., Clewell, Harvey J., Andersen, Melvin E., Valdez-Flores, Ciriaco, Sielken, Robert L.

Journal:

Toxicological Sciences

Year:

2016

Language:

english

File:

PDF, 1.24 MB

english, 2016

47

Cancer Dose-Response Modeling of Epidemiological Data on Worker Exposures to Aldrin and Dieldrin

Robert L. Sielken Jr., Robert S. Bretzlaff, Ciriaco Valdez-Flores, Donald E. Stevenson, Geed de Jong

Journal:

Year:

1999

Language:

english

File:

PDF, 1.23 MB

english, 1999

48

Cancer risk assessment for 1,3-butadiene: Dose–response modeling from an epidemiological perspective

Robert L. Sielken Jr., Ciriaco Valdez-Flores, Michael L. Gargas, Christopher R. Kirman, M. Jane Teta, Elizabeth Delzell

Journal:

Chemico-Biological Interactions

Year:

2007

Language:

english

File:

PDF, 221 KB

english, 2007

49

Dose–response implications of the University of Alabama study of lymphohematopoietic cancer among workers exposed to 1,3-butadiene and styrene in the synthetic rubber industry

Robert L. Sielken Jr, Ciriaco Valdez-Flores

Journal:

Chemico-Biological Interactions

Year:

2001

Language:

english

File:

PDF, 216 KB

english, 2001

50

An updated inhalation unit risk factor for arsenic and inorganic arsenic compounds based on a combined analysis of epidemiology studies

Erraguntla, Neeraja K., Sielken, Robert L., Valdez-Flores, Ciriaco, Grant, Roberta L.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 292 KB

english, 2012

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